| Record of the Year |
- "Use Somebody"
- Kings of Leon
- Nominees:
- "Halo"
- "I Gotta Feeling"
- "Poker Face"
- "You Belong With Me"
| Album of the Year |
- Fearless
- Taylor Swift
- Nominees:
- I Am... Sasha Fierce
- The E.N.D.
- The Fame
- Big Whiskey And The Groogrux King
| Song of the Year |
- "Single Ladies (Put A Ring On It)" (Beyonce)
- Thaddis Harrell, Beyonce Knowles, Terius Nash & Christopher Stewart
- Nominees:
- "Poker Face" (Lady Gaga)
- "Pretty Wings" (Maxwell)
- "Use Somebody" (Kings of Leon)
- "You Belong With Me" (Taylor Swift)
| Best New Artist |
- Zac Brown Band
- Nominees:
- Keri Hilson
- MGMT
- Silversun Pickups
- The Ting Tings
| Best Female Pop Vocal Performance |
- Halo
- Beyoncé
- Nominees:
- Hometown Glory
- Hot N Cold
- Sober
- You Belong With Me
| Best Male Pop Vocal Performance |
- Make It Mine
- Jason Mraz
- Nominees:
- This Time
- Love You
- If You Don't Know Me By Now
- All About The Love Again
| Best Pop Performance By A Duo Or Group With Vocals |
- I Gotta Feeling
- The Black Eyed Peas
- Nominees:
- We Weren't Born To Follow
- Never Say Never
- Sara Smile
- Kids
| Best Pop Collaboration With Vocals |
- Lucky
- Jason Mraz & Colbie Caillat
- Nominees:
- Sea Of Heartbreak
- Love Sex Magic
- Baby, It's Cold Outside
- Breathe
| Best Pop Instrumental Performance |
- Throw Down Your Heart
- Béla Fleck
- Nominees:
- Besame Mucho
- The Fire
- Phoenix Rise
- Funk Joint
| Best Pop Instrumental Album |
- Potato Hole
- Booker T. Jones
- Nominees:
- In Boston
- Legacy
- Modern Art
- Down The Wire
| Best Pop Vocal Album |
- The E.N.D.
- The Black Eyed Peas
- Nominees:
- Breakthrough
- All I Ever Wanted
- The Fray
- Funhouse
| Best Dance Recording |
- Poker Face
- Lady Gaga
- Nominees:
- Boom Boom Pow
- When Love Takes Over
- Celebration
- Womanizer
| Best Electronic/Dance Album |
- The Fame
- Lady Gaga
- Nominees:
- Divided By Night
- One Love
- Party Rock
- Yes
| Best Traditional Pop Vocal Album |
- Michael Bublé Meets Madison Square Garden
- Michael Bublé
- Nominees:
- A Swingin' Christmas
- Your Songs
- Liza's At The Palace
- American Classic
| Best Solo Rock Vocal Performance |
- Working On A Dream
- Bruce Springsteen
- Nominees:
- Beyond Here Lies Nothin'
- Change In The Weather
- Dreamer
- Fork In The Road
| Best Rock Performance By A Duo Or Group With Vocals |
- Use Somebody
- Kings Of Leon
- Nominees:
- Can't Find My Way Home
- Life In Technicolor II
- 21 Guns
- I'll Go Crazy If I Don't Go Crazy Tonight
| Best Hard Rock Performance |
- War Machine
- AC/DC
- Nominees:
- Check My Brain
- What I've Done
- The Unforgiven III
- Burn It To The Ground
| Best Metal Performance |
- Dissident Aggressor
- Judas Priest
- Nominees:
- Set To Fail
- Head Crusher
- Señor Peligro
- Hate Worldwide
| Best Rock Instrumental Performance |
- A Day In The Life
- Jeff Beck
- Nominees:
- Warped Sister
- Playing With Fire
- Mr. Surfer Goes Jazzin'
- Now We Run
| Best Rock Song |
- Use Somebody (Kings Of Leon)
- Caleb Followill, Jared Followill, Matthew Followill & Nathan Followill, songwriters
- Nominees:
- The Fixer (Pearl Jam)
- I'll Go Crazy If I Don't Go Crazy Tonight (U2)
- 21 Guns ((Green Day))
- Working On A Dream (Bruce Springsteen)
| Best Rock Album |
- 21st Century Breakdown
- Green Day
- Nominees:
- Black Ice
- Live From Madison Square Garden
- Big Whiskey And The Groogrux King
- No Line On The Horizon
| Best Alternative Music Album |
- Wolfgang Amadeus Phoenix
- Phoenix
- Nominees:
- Everything That Happens Will Happen Today
- The Open Door
- Sounds Of The Universe
- It's Blitz!
| Best Female R&B Vocal Performance |
- Single Ladies (Put A Ring On It)
- Beyoncé
- Nominees:
- It Kills Me
- That Was Then
- Goin' Thru Changes
- Lions, Tigers & Bears
| Best Male R&B Vocal Performance |
- Pretty Wings
- Maxwell
- Nominees:
- The Point Of It All
- Sobeautiful
- Under
- There Goes My Baby
| Best R&B Performance By A Duo Or Group With Vocals |
- Blame It
- Jamie Foxx & T-Pain
- Nominees:
- Chocolate High
- Ifuleave
- Higher Ground
- Love Has Finally Come At Last
| Best Traditional R&B Vocal Performance |
- At Last
- Beyoncé
- Nominees:
- Soul Music
- Don't Let Me Be Lonely Tonight
- Sow Love
- Woman Gotta Have It
| Best Urban/Alternative Performance |
- Pearls
- India.Arie & Dobet Gnahore
- Nominees:
- Daykeeper
- All Matter
- A Tale Of Two
- Blend
| Best R&B Song |
- Single Ladies (Put A Ring On It) (Beyoncé)
- Thaddis Harrell, Beyoncé Knowles, Terius Nash & Christopher Stewart, songwriters
- Nominees:
- Blame It (Jamie Foxx & T-Pain)
- Lions, Tigers & Bears (Jazmine Sullivan)
- Pretty Wings (Maxwell)
- Under (Pleasure P)
| Best R&B Album |
- Blacksummers' Night
- Maxwell
- Nominees:
- The Point Of It All
- Testimony: Vol. 2, Love & Politics
- Turn Me Loose
- Uncle Charlie
| Best Contemporary R&B Album |
- I Am...Sasha Fierce
- Beyoncé
- Nominees:
- Intuition
- The Introduction Of Marcus Cooper
- Ready
- Thr33 Ringz
| Best Rap Solo Performance |
- D.O.A. (Death Of Auto-Tune)
- Jay-Z
- Nominees:
- Best I Ever Had
- Beautiful
- Day 'N' Nite
- Casa Bey
| Best Rap Performance By A Duo Or Group |
- Crack A Bottle
- Eminem, Dr. Dre & 50 Cent
- Nominees:
- Too Many Rappers
- Money Goes, Honey Stay
- Make Her Say
- Amazing
| Best Rap/Sung Collaboration |
- Run This Town
- Jay-Z, Rihanna & Kanye West
- Nominees:
- Ego
- Knock You Down
- I'm On A Boat
- Dead And Gone
| Best Rap Song |
- Run This Town (Jay-Z, Rihanna & Kanye West)
- Shawn Carter, R. Fenty, M. Riddick, Kanye West & E. Wilson, songwriters
- Nominees:
- Best I Ever Had (Drake)
- Day 'N' Nite (Kid Cudi)
- Dead And Gone (T.I. & Justin Timberlake)
- D.O.A. (Death Of Auto-Tune) (Jay-Z)
| Best Rap Album |
- Relapse
- Eminem
- Nominees:
- Universal Mind Control
- R.O.O.T.S.
- The Ecstatic
- The Renaissance
| Best Female Country Vocal Performance |
- White Horse
- Taylor Swift
- Nominees:
- Dead Flowers
- I Just Call You Mine
- Just A Dream
- Solitary Thinkin'
| Best Male Country Vocal Performance |
- Sweet Thing
- Keith Urban
- Nominees:
- All I Ask For Anymore
- People Are Crazy
- High Cost Of Living
- Living For The Night
| Best Country Performance By A Duo Or Group With Vocals |
- I Run To You
- Lady Antebellum
- Nominees:
- Cowgirls Don't Cry
- Chicken Fried
- Here Comes Goodbye
- It Happens
| Best Country Collaboration With Vocals |
- I Told You So
- Carrie Underwood & Randy Travis
- Nominees:
- Beautiful World
- Down The Road
- Start A Band
- Everything But Quits
| Best Country Instrumental Performance |
- Producer's Medley
- Steve Wariner
- Nominees:
- Under The (Five) Wire
- The Crystal Merchant
- Mansinneedof
| Best Country Song |
- White Horse (Taylor Swift)
- Liz Rose & Taylor Swift, songwriters
- Nominees:
- All I Ask For Anymore (Trace Adkins)
- High Cost Of Living (Jamey Johnson)
- I Run To You (Lady Antebellum)
- People Are Crazy (Billy Currington)
| Best Country Album |
- Fearless
- Taylor Swift
- Nominees:
- The Foundation
- Twang
- Defying Gravity
- Call Me Crazy
