Lincoln leads the Oscar® pack with 12 nominations, including Best Picture.
Life Of Pi closely followed with 11 nods. Les Misérables got eight, and so did Silver Linings Playbook.
INSIDE EDITION's Jim Moret spoke to MacFarlane.
"We wanted to present relatively dry information in a fun, peppy way," said MacFarlane.
Moret asked, "Are you nervous?"
"Not as much as I should be. I guess that's a bad sign, isn't it?" said MacFarlane.
There were audible gasps in the crowd as the Best Director nominations wrapped up. Quentin Tarantino was snubbed for Django Unchained. So was Ben Affleck for Argo.
The Best Actor nominees are Daniel Day Lewis for Lincoln, Bradley Cooper for Silver Linings Playbook, Hugh Jackman for Les Miserables, Joaquin Phoenix for The Master and Denzel Washington for Flight.
Anne Hathaway got a Best Supporting Actress nod for Les Mis and is considered the front runner.
MacFarlane also got a nomination for Best Song, from his comedy, Ted. MacFarlane joked, "That's kinda cool, I got nominated. I get to go to the Oscars® now."