Actor Ed Helms from TV's The Office used a song to inspire the graduating class at the University of Virginia.
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He sang, "This little light of mine, I'm gonna let it shine."
Maya Rudolph impersonated Oprah Winfrey during her commencement address at Tulane University in New Orleans.
She said, "Look under your seats because you are all leaving here today with a college diploma! You get a diploma! You, sir, you get a diploma! We're all getting diplomas!"
Former president George W. Bush cracked a joke as he addressed graduates at Southern Methodist University in Dallas.
He said, "Those of you who are graduating this afternoon with high honors awards and distinctions, I say well done. As I like to tell the 'C' students, you, too, can be president."
Stephen Colbert addressed graduates at Wake Forest University.
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He told the students, "You look amazing, weird that you all are wearing the same thing. Even the accessories."
Finally, all Matthew McConaughey had to do was take off his jacket to get the crowd going at the University of Houston.
Watch Below: University Cancels Common as Graduation Speaker Over 15-Year-Old Song