Jamie Brewer has shared the spotlight with some of the biggest names in Hollywood, like Kathy Bates, Angela Bassett and Jessica Lange. Now, the 33-year-old actress thought to be the first lead in an off-Broadway production to have Down syndrome. Her list of credits includes a recurring role on the hit TV show "American Horror Story." But perhaps her most challenging role yet is live on stage in "Amy and the Orphans." InsideEdition.com's Keleigh Nealon (http://twitter.com/KeleighNealon) has more.