Oprah says she is not running for president. She made the revelation in the latest ‘InStyle’ magazine cover story. “I've always felt very secure and confident with myself in knowing what I could do and what I could not. It's not something that interests me. I don't have the DNA for it,” she said. The interview was conducted three weeks before her fiery Golden Globes speech that triggered the buzz about a possible 2020 presidential bid. It remains unclear if Winfrey has since changed her mind.